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Clostridial C3 Toxins Target Monocytes/Macrophages and Modulate Their Functions
The C3 enzymes from Clostridium (C.) botulinum (C3bot) and Clostridium limosum (C3lim) are single chain protein toxins of about 25 kDa that mono-ADP-ribosylate Rho-A, -B, and -C in the cytosol of mammalian cells. We discovered that both C3 proteins are selectively internalized into the cytosol of mo...
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| Yayımlandı: | Front Immunol |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Frontiers Media S.A.
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4485225/ https://ncbi.nlm.nih.gov/pubmed/26175735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00339 |
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