Loading...

A Recombinant Fusion Toxin Based on Enzymatic Inactive C3bot1 Selectively Targets Macrophages

BACKGROUND: The C3bot1 protein (∼23 kDa) from Clostridium botulinum ADP-ribosylates and thereby inactivates Rho. C3bot1 is selectively taken up into the cytosol of monocytes/macrophages but not of other cell types such as epithelial cells or fibroblasts. Most likely, the internalization occurs by a...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Dmochewitz, Lydia, Förtsch, Christina, Zwerger, Christian, Vaeth, Martin, Felder, Edward, Huber-Lang, Markus, Barth, Holger
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549961/
https://ncbi.nlm.nih.gov/pubmed/23349915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054517
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!