Rho-inhibiting C2IN-C3 fusion toxin inhibits chemotactic recruitment of human monocytes ex vivo and in mice in vivo

Bacterial protein toxins became valuable molecular tools for the targeted modulation of cell functions in experimental pharmacology and attractive therapeutics because of their potent and specific mode of action in human cells. C2IN-C3lim, a recombinant fusion toxin (~50 kDa) of the Rho-inhibiting C...

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Detalhes bibliográficos
Publicado no:Arch Toxicol
Main Authors: Martin, Tobias, Möglich, Amelie, Felix, Ina, Förtsch, Christina, Rittlinger, Anne, Palmer, Annette, Denk, Stephanie, Schneider, Julian, Notbohm, Lena, Vogel, Mona, Geiger, Hartmut, Paschke, Stephan, Huber-Lang, Markus, Barth, Holger
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2017
Assuntos:
Molecular Toxicology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773661/
https://ncbi.nlm.nih.gov/pubmed/28924833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-017-2058-y
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