Mouse Macrophages Completely Lacking Rho Subfamily GTPases (RhoA, RhoB, and RhoC) Have Severe Lamellipodial Retraction Defects, but Robust Chemotactic Navigation and Altered Motility

RhoA is thought to be essential for coordination of the membrane protrusions and retractions required for immune cell motility and directed migration. Whether the subfamily of Rho (Ras homolog) GTPases (RhoA, RhoB, and RhoC) is actually required for the directed migration of primary cells is difficu...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Königs, Volker, Jennings, Richard, Vogl, Thomas, Horsthemke, Markus, Bachg, Anne C., Xu, Yan, Grobe, Kay, Brakebusch, Cord, Schwab, Albrecht, Bähler, Martin, Knaus, Ulla G., Hanley, Peter J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2014
Gaiak:
Cell Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215254/
https://ncbi.nlm.nih.gov/pubmed/25213860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.563270
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