Long-circulating siRNA nanoparticles for validating Prohibitin1-targeted non-small cell lung cancer treatment

RNA interference (RNAi) represents a promising strategy for identification and validation of putative therapeutic targets and for treatment of a myriad of important human diseases including cancer. However, the effective systemic in vivo delivery of small interfering RNA (siRNA) to tumors remains a...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Zhu, Xi, Xu, Yingjie, Solis, Luisa M., Tao, Wei, Wang, Liangzhe, Behrens, Carmen, Xu, Xiaoyang, Zhao, Lili, Liu, Danny, Wu, Jun, Zhang, Ning, Wistuba, Ignacio I., Farokhzad, Omid C., Zetter, Bruce R., Shi, Jinjun
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2015
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485147/
https://ncbi.nlm.nih.gov/pubmed/26056316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505629112
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