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The Origin of Mutants Under Selection: How Natural Selection Mimics Mutagenesis (Adaptive Mutation)

Selection detects mutants but does not cause mutations. Contrary to this dictum, Cairns and Foster plated a leaky lac mutant of Escherichia coli on lactose medium and saw revertant (Lac(+)) colonies accumulate with time above a nongrowing lawn. This result suggested that bacteria might mutagenize th...

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Détails bibliographiques
Publié dans:Cold Spring Harb Perspect Biol
Auteurs principaux: Maisnier-Patin, Sophie, Roth, John R.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484973/
https://ncbi.nlm.nih.gov/pubmed/26134316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a018176
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