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Selective Inbreeding: Genetic Crosses Drive Apparent Adaptive Mutation in the Cairns-Foster System of Escherichia coli
The Escherichia coli system of Cairns and Foster employs a lac frameshift mutation that reverts rarely (10(−9)/cell/division) during unrestricted growth. However, when 10(8) cells are plated on lactose medium, the nongrowing lawn produces ∼50 Lac(+) revertant colonies that accumulate linearly with t...
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| Publicado no: | Genetics |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7017022/ https://ncbi.nlm.nih.gov/pubmed/31810989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.119.302754 |
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