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Pathways of Genetic Adaptation: Multistep Origin of Mutants Under Selection Without Induced Mutagenesis in Salmonella enterica

In several bacterial systems, mutant cell populations plated on growth-restricting medium give rise to revertant colonies that accumulate over several days. One model suggests that nongrowing parent cells mutagenize their own genome and thereby create beneficial mutations (stress-induced mutagenesis...

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Detalles Bibliográficos
Main Authors: Quiñones-Soto, Semarhy, Reams, Andrew B., Roth, John R.
Formato: Artigo
Idioma:Inglês
Publicado: Genetics Society of America 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522171/
https://ncbi.nlm.nih.gov/pubmed/22887815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.142158
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