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FOXO1/3 and PTEN Depletion in Granulosa Cells Promotes Ovarian Granulosa Cell Tumor Development

The forkhead box (FOX), FOXO1 and FOXO3, transcription factors regulate multiple functions in mammalian cells. Selective inactivation of the Foxo1 and Foxo3 genes in murine ovarian granulosa cells severely impairs follicular development and apoptosis causing infertility, and as shown here, granulosa...

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書目詳細資料
發表在:Mol Endocrinol
Main Authors: Liu, Zhilin, Ren, Yi A., Pangas, Stephanie A., Adams, Jaye, Zhou, Wei, Castrillon, Diego H., Wilhelm, Dagmar, Richards, JoAnne S.
格式: Artigo
語言:Inglês
出版: Endocrine Society 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484779/
https://ncbi.nlm.nih.gov/pubmed/26061565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1103
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