FOXO1/3 and PTEN Depletion in Granulosa Cells Promotes Ovarian Granulosa Cell Tumor Development

The forkhead box (FOX), FOXO1 and FOXO3, transcription factors regulate multiple functions in mammalian cells. Selective inactivation of the Foxo1 and Foxo3 genes in murine ovarian granulosa cells severely impairs follicular development and apoptosis causing infertility, and as shown here, granulosa...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Endocrinol
Egile Nagusiak: Liu, Zhilin, Ren, Yi A., Pangas, Stephanie A., Adams, Jaye, Zhou, Wei, Castrillon, Diego H., Wilhelm, Dagmar, Richards, JoAnne S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Endocrine Society 2015
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484779/
https://ncbi.nlm.nih.gov/pubmed/26061565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2015-1103
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