Calnexin induces expansion of antigen-specific CD4(+) T cells that confer immunity to fungal ascomycetes via conserved epitopes

Fungal infections remain a threat due to the lack of broad spectrum fungal vaccines and protective antigens. Recent studies showed that attenuated Blastomyces dermatitidis confers protection via T cell recognition of an unknown, but conserved antigen. Using transgenic CD4+ T cells recognizing this a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Host Microbe
Egile Nagusiak: Wüthrich, Marcel, Brandhorst, Tristan T., Sullivan, Thomas D., Filutowicz, Hanna, Sterkel, Alana, Stewart, Douglas, Li, Mengyi, Lerksuthirat, Tassanee, LeBert, Vanessa, Shen, Zu Ting, Ostroff, Gary, Deepe, George S., Hung, Chiung Yu, Cole, Garry, Walter, Jennifer A., Jenkins, Marc K., Klein, Bruce
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484745/
https://ncbi.nlm.nih.gov/pubmed/25800545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2015.02.009
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