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Deficient brain insulin signalling pathway in Alzheimer’s disease and diabetes
Brain glucose metabolism is impaired in Alzheimer’s disease (AD), the most common form of dementia. Type 2 diabetes mellitus (T2DM) is reported to increase the risk for dementia, including AD, but the underlying mechanism is not understood. Here, we investigated the brain insulin–PI3K–AKT signalling...
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| Publicado no: | J Pathol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4484598/ https://ncbi.nlm.nih.gov/pubmed/21598254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.2912 |
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