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Down-regulation of cAMP-dependent protein kinase by over-activated calpain in Alzheimer disease brain
Impaired cognition and memory may be associated with down-regulation of cAMP-response element-binding protein (CREB) in the brain in patients with Alzheimer disease, but the molecular mechanism leading to the down-regulation is not understood. In this study, we found a selective reduction in the lev...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2262109/ https://ncbi.nlm.nih.gov/pubmed/17908236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2007.04942.x |
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