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Single-molecule analysis of Mss116-mediated group II intron folding

DEAD-box helicases are conserved enzymes involved in nearly all aspects of RNA metabolism, but their mechanisms of action remain unclear. Here, we investigated the mechanism of the DEAD-box protein Mss116 on its natural substrate, the group II intron ai5γ. Group II introns are structurally complex c...

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Bibliographic Details
Published in:Nature
Main Authors: Karunatilaka, Krishanthi S., Solem, Amanda, Pyle, Anna Marie, Rueda, David
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484588/
https://ncbi.nlm.nih.gov/pubmed/20944626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09422
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