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The Brace for a Growing Scaffold: Mss116 Protein Promotes RNA Folding by Stabilizing an Early Assembly Intermediate

The ai5γ group II intron requires a protein cofactor to facilitate native folding in the cell. Yeast protein Mss116 greatly accelerates intron folding under near-physiological conditions both in vivo and in vitro. Although the effect of Mss116 on the kinetics of ai5γ ribozyme folding and catalysis h...

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Publicado en:J Mol Biol
Autores principales: Fedorova, Olga, Pyle, Anna Marie
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4419380/
https://ncbi.nlm.nih.gov/pubmed/22705286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.05.037
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