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Dual roles for the Mss116 cofactor during splicing of the ai5γ group II intron

The autocatalytic group II intron ai5γ from Saccharomyces cerevisiae self-splices under high-salt conditions in vitro, but requires the assistance of the DEAD-box protein Mss116 in vivo and under near-physiological conditions in vitro. Here, we show that Mss116 influences the folding mechanism in se...

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Autors principals: Zingler, Nora, Solem, Amanda, Pyle, Anna Marie
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965245/
https://ncbi.nlm.nih.gov/pubmed/20554854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq530
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