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A kinetic intermediate that regulates proper folding of a group II intron RNA
The D135 group II intron ribozyme follows a unique folding pathway that is direct and appears to be devoid of kinetic traps. During the earliest stages of folding, D135 collapses slowly to a compact intermediate, and all subsequent assembly events are rapid. Collapse of intron Domain 1 (D1) has been...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2735237/ https://ncbi.nlm.nih.gov/pubmed/18022197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.10.052 |
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