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Proteasomes: Isolation and Activity Assays
In eukaryotes, damaged or unneeded proteins are typically degraded by the ubiquitin-proteasome system. In this system, the protein substrate is often first covalently modified with a chain of ubiquitin polypeptides. This chain serves as a signal for delivery to the 26S proteasome, a 2.5 MDa, ATP-dep...
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| Udgivet i: | Curr Protoc Cell Biol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4484579/ https://ncbi.nlm.nih.gov/pubmed/26061243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471143030.cb0343s67 |
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