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Proteasomes: Isolation and Activity Assays

In eukaryotes, damaged or unneeded proteins are typically degraded by the ubiquitin-proteasome system. In this system, the protein substrate is often first covalently modified with a chain of ubiquitin polypeptides. This chain serves as a signal for delivery to the 26S proteasome, a 2.5 MDa, ATP-dep...

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Détails bibliographiques
Publié dans:Curr Protoc Cell Biol
Auteurs principaux: Li, Yanjie, Tomko, Robert J., Hochstrasser, Mark
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484579/
https://ncbi.nlm.nih.gov/pubmed/26061243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471143030.cb0343s67
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