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Molecular Architecture and Assembly of the Eukaryotic Proteasome
The eukaryotic ubiquitin-proteasome system is responsible for most cellular quality-control and regulatory protein degradation. Its substrates, which are usually modified by polymers of ubiquitin, are ultimately degraded by the 26S proteasome. This 2.6 MDa protein complex is separated into a barrel-...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3827779/ https://ncbi.nlm.nih.gov/pubmed/23495936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-biochem-060410-150257 |
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