LLL12, a novel small inhibitor targeting STAT3 for hepatocellular carcinoma therapy

The constitutive activation of signal transducer and activator of transcription 3 (STAT3) is frequently detected in clinical incidences of hepatocellular carcinoma (HCC) but not in normal human hepatocytes. STAT3 signaling plays pivotal roles in angiogenesis, survival, metastasis, and growth of HCC....

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Vydáno v:Oncotarget
Hlavní autoři: Zuo, Mingxin, Li, Chenglong, Lin, Jiayuh, Javle, Milind
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2015
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484430/
https://ncbi.nlm.nih.gov/pubmed/25883212
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