Brachyury and SMAD signalling collaboratively orchestrate distinct mesoderm and endoderm gene regulatory networks in differentiating human embryonic stem cells

The transcription factor brachyury (T, BRA) is one of the first markers of gastrulation and lineage specification in vertebrates. Despite its wide use and importance in stem cell and developmental biology, its functional genomic targets in human cells are largely unknown. Here, we use differentiatin...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Development
Main Authors: Faial, Tiago, Bernardo, Andreia S., Mendjan, Sasha, Diamanti, Evangelia, Ortmann, Daniel, Gentsch, George E., Mascetti, Victoria L., Trotter, Matthew W. B., Smith, James C., Pedersen, Roger A.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists 2015
Fag:
Stem Cells and Regeneration
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483767/
https://ncbi.nlm.nih.gov/pubmed/26015544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.117838
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker