Proteinuria Increases Plasma Phosphate by Altering Its Tubular Handling

Proteinuria and hyperphosphatemia are cardiovascular risk factors independent of GFR. We hypothesized that proteinuria induces relative phosphate retention via increased proximal tubule phosphate reabsorption. To test the clinical relevance of this hypothesis, we studied phosphate handling in nephro...

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Pubblicato in:J Am Soc Nephrol
Autori principali: de Seigneux, Sophie, Courbebaisse, Marie, Rutkowski, Joseph M., Wilhelm-Bals, Alexandra, Metzger, Marie, Khodo, Stellor Nlandu, Hasler, Udo, Chehade, Hassib, Dizin, Eva, Daryadel, Arezoo, Stengel, Bénedicte, Girardin, E., Prié, Dominique, Wagner, Carsten A., Scherer, Philipp E., Martin, Pierre-Yves, Houillier, Pascal, Feraille, Eric
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2015
Soggetti:
Basic Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483577/
https://ncbi.nlm.nih.gov/pubmed/25349200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014010104
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