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NADPH oxidase 4 deficiency increases tubular cell death during acute ischemic reperfusion injury
NADPH oxidase 4 (NOX4) is highly expressed in kidney proximal tubular cells. NOX4 constitutively produces hydrogen peroxide, which may regulate important pro-survival pathways. Renal ischemia reperfusion injury (IRI) is a classical model mimicking human ischemic acute tubular necrosis. We hypothesiz...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5141508/ https://ncbi.nlm.nih.gov/pubmed/27924932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38598 |
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