The NADPH oxidase Nox4 restricts the replicative lifespan of human endothelial cells

The free radical theory of aging proposes that ROS (reactive oxygen species) are major driving forces of aging, and are also critically involved in cellular senescence. Besides the mitochondrial respiratory chain, alternative sources of ROS have been described that might contribute to cellular senes...

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Autors principals: Lener, Barbara, Kozieł, Rafał, Pircher, Haymo, Hütter, Eveline, Greussing, Ruth, Herndler-Brandstetter, Dietmar, Hermann, Martin, Unterluggauer, Hermann, Jansen-Dürr, Pidder
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2009
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762686/
https://ncbi.nlm.nih.gov/pubmed/19681754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20090666
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