The NADPH oxidase Nox4 restricts the replicative lifespan of human endothelial cells

The free radical theory of aging proposes that ROS (reactive oxygen species) are major driving forces of aging, and are also critically involved in cellular senescence. Besides the mitochondrial respiratory chain, alternative sources of ROS have been described that might contribute to cellular senes...

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Detalhes bibliográficos
Main Authors: Lener, Barbara, Kozieł, Rafał, Pircher, Haymo, Hütter, Eveline, Greussing, Ruth, Herndler-Brandstetter, Dietmar, Hermann, Martin, Unterluggauer, Hermann, Jansen-Dürr, Pidder
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762686/
https://ncbi.nlm.nih.gov/pubmed/19681754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20090666
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