The NADPH oxidase Nox4 restricts the replicative lifespan of human endothelial cells

The free radical theory of aging proposes that ROS (reactive oxygen species) are major driving forces of aging, and are also critically involved in cellular senescence. Besides the mitochondrial respiratory chain, alternative sources of ROS have been described that might contribute to cellular senes...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lener, Barbara, Kozieł, Rafał, Pircher, Haymo, Hütter, Eveline, Greussing, Ruth, Herndler-Brandstetter, Dietmar, Hermann, Martin, Unterluggauer, Hermann, Jansen-Dürr, Pidder
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Portland Press Ltd. 2009
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762686/
https://ncbi.nlm.nih.gov/pubmed/19681754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20090666
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