NADPH Oxidase 4 Deficiency Reduces Aquaporin-2 mRNA Expression in Cultured Renal Collecting Duct Principal Cells via Increased PDE3 and PDE4 Activity

The final control of renal water reabsorption occurs in the collecting duct (CD) and relies on regulated expression of aquaporin-2 (AQP2) in principal CD cells. AQP2 transcription is primarily induced by type 2 vasopressin receptor (V(2)R)-cAMP-protein kinase A (PKA) signaling but also by other fact...

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Detalhes bibliográficos
Main Authors: Féraille, Eric, Dizin, Eva, Roth, Isabelle, Derouette, Jean-Paul, Szanto, Ildiko, Martin, Pierre-Yves, de Seigneux, Sophie, Hasler, Udo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900718/
https://ncbi.nlm.nih.gov/pubmed/24466344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087239
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