NADPH Oxidase 4 Deficiency Reduces Aquaporin-2 mRNA Expression in Cultured Renal Collecting Duct Principal Cells via Increased PDE3 and PDE4 Activity

The final control of renal water reabsorption occurs in the collecting duct (CD) and relies on regulated expression of aquaporin-2 (AQP2) in principal CD cells. AQP2 transcription is primarily induced by type 2 vasopressin receptor (V(2)R)-cAMP-protein kinase A (PKA) signaling but also by other fact...

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Autores principales: Féraille, Eric, Dizin, Eva, Roth, Isabelle, Derouette, Jean-Paul, Szanto, Ildiko, Martin, Pierre-Yves, de Seigneux, Sophie, Hasler, Udo
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900718/
https://ncbi.nlm.nih.gov/pubmed/24466344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087239
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