Phase II study of panobinostat in combination with bevacizumab for recurrent glioblastoma and anaplastic glioma

BACKGROUND: Panobinostat is a histone deacetylase inhibitor with antineoplastic and antiangiogenic effects in glioma that may work synergistically with bevacizumab. We conducted a multicenter phase II trial of panobinostat combined with bevacizumab in patients with recurrent high-grade glioma (HGG)....

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Neuro Oncol
Egile Nagusiak: Lee, Eudocia Q., Reardon, David A., Schiff, David, Drappatz, Jan, Muzikansky, Alona, Grimm, Sean A., Norden, Andrew D., Nayak, Lakshmi, Beroukhim, Rameen, Rinne, Mikael L., Chi, Andrew S., Batchelor, Tracy T., Hempfling, Kelly, McCluskey, Christine, Smith, Katrina H., Gaffey, Sarah C., Wrigley, Brendan, Ligon, Keith L., Raizer, Jeffrey J., Wen, Patrick Y.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2015
Gaiak:
Clinical Investigations
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483124/
https://ncbi.nlm.nih.gov/pubmed/25572329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou350
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