Adult mouse subventricular zones stimulate glioblastoma stem cells specific invasion through CXCL12/CXCR4 signaling

BACKGROUND: Patients with glioblastoma multiforme (GBM) have an overall median survival of 15 months. This catastrophic survival rate is the consequence of systematic relapses that could arise from remaining glioblastoma stem cells (GSCs) left behind after surgery. We previously demonstrated that GS...

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Publicat a:Neuro Oncol
Autors principals: Goffart, Nicolas, Kroonen, Jérôme, Di Valentin, Emmanuel, Dedobbeleer, Matthias, Denne, Alexandre, Martinive, Philippe, Rogister, Bernard
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
Matèries:
Basic and Translational Investigations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483049/
https://ncbi.nlm.nih.gov/pubmed/25085362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou144
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