Adult mouse subventricular zones stimulate glioblastoma stem cells specific invasion through CXCL12/CXCR4 signaling

BACKGROUND: Patients with glioblastoma multiforme (GBM) have an overall median survival of 15 months. This catastrophic survival rate is the consequence of systematic relapses that could arise from remaining glioblastoma stem cells (GSCs) left behind after surgery. We previously demonstrated that GS...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Goffart, Nicolas, Kroonen, Jérôme, Di Valentin, Emmanuel, Dedobbeleer, Matthias, Denne, Alexandre, Martinive, Philippe, Rogister, Bernard
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2015
Soggetti:
Basic and Translational Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483049/
https://ncbi.nlm.nih.gov/pubmed/25085362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou144
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