Adult mouse subventricular zones stimulate glioblastoma stem cells specific invasion through CXCL12/CXCR4 signaling

BACKGROUND: Patients with glioblastoma multiforme (GBM) have an overall median survival of 15 months. This catastrophic survival rate is the consequence of systematic relapses that could arise from remaining glioblastoma stem cells (GSCs) left behind after surgery. We previously demonstrated that GS...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Goffart, Nicolas, Kroonen, Jérôme, Di Valentin, Emmanuel, Dedobbeleer, Matthias, Denne, Alexandre, Martinive, Philippe, Rogister, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483049/
https://ncbi.nlm.nih.gov/pubmed/25085362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou144
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