Adult mouse subventricular zones stimulate glioblastoma stem cells specific invasion through CXCL12/CXCR4 signaling

BACKGROUND: Patients with glioblastoma multiforme (GBM) have an overall median survival of 15 months. This catastrophic survival rate is the consequence of systematic relapses that could arise from remaining glioblastoma stem cells (GSCs) left behind after surgery. We previously demonstrated that GS...

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Vydáno v:Neuro Oncol
Hlavní autoři: Goffart, Nicolas, Kroonen, Jérôme, Di Valentin, Emmanuel, Dedobbeleer, Matthias, Denne, Alexandre, Martinive, Philippe, Rogister, Bernard
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
Basic and Translational Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483049/
https://ncbi.nlm.nih.gov/pubmed/25085362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou144
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