Machine Learning Models and Pathway Genome Data Base for Trypanosoma cruzi Drug Discovery

BACKGROUND: Chagas disease is a neglected tropical disease (NTD) caused by the eukaryotic parasite Trypanosoma cruzi. The current clinical and preclinical pipeline for T. cruzi is extremely sparse and lacks drug target diversity. METHODOLOGY/PRINCIPAL FINDINGS: In the present study we developed a co...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS Negl Trop Dis
Auteurs principaux: Ekins, Sean, Lage de Siqueira-Neto, Jair, McCall, Laura-Isobel, Sarker, Malabika, Yadav, Maneesh, Ponder, Elizabeth L., Kallel, E. Adam, Kellar, Danielle, Chen, Steven, Arkin, Michelle, Bunin, Barry A., McKerrow, James H., Talcott, Carolyn
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482694/
https://ncbi.nlm.nih.gov/pubmed/26114876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003878
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