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Are Outcome-Adaptive Allocation Trials Ethical?

Randomization is firmly established as a cornerstone of clinical trial methodology. Yet, the ethics of randomization continues to generate controversy. The default, and most efficient, allocation scheme randomizes patients equally (1:1) across all arms of study. However, many randomized trials are u...

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Detalhes bibliográficos
Publicado no:Clin Trials
Main Authors: Hey, Spencer Phillips, Kimmelman, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482671/
https://ncbi.nlm.nih.gov/pubmed/25649106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774514563583
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