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The questionable use of unequal allocation in confirmatory trials
Randomization is the standard means for addressing known and unknown confounders within the patient population in clinical trials. Although random assignment to treatment arms on a 1:1 basis has long been the norm, many 2-armed confirmatory trials now use unequal allocation schemes where the number...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Lippincott Williams & Wilkins
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3873626/ https://ncbi.nlm.nih.gov/pubmed/24306005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/01.wnl.0000438226.10353.1c |
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