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Ethics, Error, and Initial Trials of Efficacy
Concerns about the frequency of failure in late stage drug development have prompted a series of proposals for improving the positive predictivity of trials where clinical activity is first evaluated—typically phase 2 trials. However, many proposed reforms entail ethical and social tradeoffs that mi...
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| Veröffentlicht in: | Sci Transl Med |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4516405/ https://ncbi.nlm.nih.gov/pubmed/23658242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3005684 |
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