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Are Outcome-Adaptive Allocation Trials Ethical?

Randomization is firmly established as a cornerstone of clinical trial methodology. Yet, the ethics of randomization continues to generate controversy. The default, and most efficient, allocation scheme randomizes patients equally (1:1) across all arms of study. However, many randomized trials are u...

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Podrobná bibliografie
Vydáno v:Clin Trials
Hlavní autoři: Hey, Spencer Phillips, Kimmelman, Jonathan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482671/
https://ncbi.nlm.nih.gov/pubmed/25649106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774514563583
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