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Growth Factor-Induced Resistance to Tamoxifen is Associated with a Mutation of Estrogen Receptor α and its Phosphorylation at Serine 305
Estrogens play a crucial role in breast tumor growth, which is the rationale for the use of antiestrogens, such as tamoxifen, in women with estrogen receptor (ER)-α-positive breast cancer. However hormone resistance is a major clinical problem. Altered growth factor signaling to the ERα pathway has...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Breast Cancer Res Treat |
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| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2009
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4482256/ https://ncbi.nlm.nih.gov/pubmed/19205871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-009-0334-0 |
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