Loss of Rho GDIα and Resistance to Tamoxifen via Effects on Estrogen Receptor α

BACKGROUND: Estrogen receptor (ER) α is a successful therapeutic target in breast cancer, but patients eventually develop resistance to antiestrogens such as tamoxifen. METHODS: To identify genes whose expression was associated with the development of tamoxifen resistance and metastasis, we used mic...

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Autori principali: Barone, Ines, Brusco, Lauren, Gu, Guowei, Selever, Jennifer, Beyer, Amanda, Covington, Kyle R., Tsimelzon, Anna, Wang, Tao, Hilsenbeck, Susan G., Chamness, Gary C., Andò, Sebastiano, Fuqua, Suzanne A.W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071355/
https://ncbi.nlm.nih.gov/pubmed/21447808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djr058
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