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Insights into how phosphorylation of estrogen receptor at serine 305 modulates tamoxifen activity in breast cancer

Estrogen receptor (ER) is the most important factor in the pathophysiology of breast cancer. Consequently, modulation of ER activity has been exploited to develop drugs against ER+ breast cancer, such as tamoxifen, referred to as endocrine therapies. With deeper understanding of ER mechanism of acti...

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Detalhes bibliográficos
Publicado no:Mol Cell Endocrinol
Main Authors: Kastrati, Irida, Semina, Svetlana, Gordon, Benjamin, Smart, Emily
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368394/
https://ncbi.nlm.nih.gov/pubmed/30659843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2019.01.014
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