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A method for mutagenesis of mouse mtDNA and a resource of mouse mtDNA mutations for modeling human pathological conditions

Mutations in human mitochondrial DNA (mtDNA) can cause mitochondrial disease and have been associated with neurodegenerative disorders, cancer, diabetes and aging. Yet our progress toward delineating the precise contributions of mtDNA mutations to these conditions is impeded by the limited availabil...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Fayzulin, Rafik Z., Perez, Michael, Kozhukhar, Natalia, Spadafora, Domenico, Wilson, Glenn L., Alexeyev, Mikhail F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482060/
https://ncbi.nlm.nih.gov/pubmed/25820427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv140
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