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A method for mutagenesis of mouse mtDNA and a resource of mouse mtDNA mutations for modeling human pathological conditions

Mutations in human mitochondrial DNA (mtDNA) can cause mitochondrial disease and have been associated with neurodegenerative disorders, cancer, diabetes and aging. Yet our progress toward delineating the precise contributions of mtDNA mutations to these conditions is impeded by the limited availabil...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Fayzulin, Rafik Z., Perez, Michael, Kozhukhar, Natalia, Spadafora, Domenico, Wilson, Glenn L., Alexeyev, Mikhail F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482060/
https://ncbi.nlm.nih.gov/pubmed/25820427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv140
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