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A Metallacycle Fragmentation Strategy for Vinyl Transfer from Enol Carboxylates to Secondary Alcohol C-H Bonds via Osmium or Ruthenium Catalyzed Transfer Hydrogenation

A strategy for catalytic vinyl transfer from enol carboxylates to activated secondary alcohol C-H bonds is described. Using XPhos-modified ruthenium(0) or osmium(0) complexes, enol carboxylate-carbonyl oxidative coupling forms transient β-carboxy-oxametallacycles, which eliminate carboxylate to deli...

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Bibliographic Details
Published in:J Am Chem Soc
Main Authors: Park, Boyoung Y., Luong, Tom, Sato, Hiroki, Krische, Michael J.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481174/
https://ncbi.nlm.nih.gov/pubmed/26066660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b04688
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