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Widespread intron retention diversifies most cancer transcriptomes
BACKGROUND: Somatic mutations affecting components of the RNA splicing machinery occur with high frequencies across many tumor types. These mutations give rise to distinct alterations in normal splice site and exon recognition, such as unusual 3′ splice site preferences, that likely contribute to tu...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Genome Med |
|---|---|
| Prif Awduron: | , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
BioMed Central
2015
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4480902/ https://ncbi.nlm.nih.gov/pubmed/26113877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-015-0168-9 |
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