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Widespread intron retention diversifies most cancer transcriptomes
BACKGROUND: Somatic mutations affecting components of the RNA splicing machinery occur with high frequencies across many tumor types. These mutations give rise to distinct alterations in normal splice site and exon recognition, such as unusual 3′ splice site preferences, that likely contribute to tu...
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| Publicado no: | Genome Med |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4480902/ https://ncbi.nlm.nih.gov/pubmed/26113877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-015-0168-9 |
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