Critical illness-induced bone loss is related to deficient autophagy and histone hypomethylation

BACKGROUND: Survivors of critical illness are at increased risk of fractures. This may be due to increased osteoclast formation during critical illness, leading to trabecular bone loss. Such bone loss has also been observed in Paget’s disease, and has been related to deficient autophagy. Deficient a...

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Bibliografiske detaljer
Udgivet i:Intensive Care Med Exp
Main Authors: Owen, Helen C, Vanhees, Ineke, Gunst, Jan, Van Cromphaut, Sophie, Van den Berghe, Greet
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2015
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480347/
https://ncbi.nlm.nih.gov/pubmed/26215816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40635-015-0052-3
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