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Critical illness-induced bone loss is related to deficient autophagy and histone hypomethylation

BACKGROUND: Survivors of critical illness are at increased risk of fractures. This may be due to increased osteoclast formation during critical illness, leading to trabecular bone loss. Such bone loss has also been observed in Paget’s disease, and has been related to deficient autophagy. Deficient a...

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Bibliographische Detailangaben
Veröffentlicht in:Intensive Care Med Exp
Hauptverfasser: Owen, Helen C, Vanhees, Ineke, Gunst, Jan, Van Cromphaut, Sophie, Van den Berghe, Greet
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480347/
https://ncbi.nlm.nih.gov/pubmed/26215816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40635-015-0052-3
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