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Critical illness-induced bone loss is related to deficient autophagy and histone hypomethylation

BACKGROUND: Survivors of critical illness are at increased risk of fractures. This may be due to increased osteoclast formation during critical illness, leading to trabecular bone loss. Such bone loss has also been observed in Paget’s disease, and has been related to deficient autophagy. Deficient a...

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書目詳細資料
發表在:Intensive Care Med Exp
Main Authors: Owen, Helen C, Vanhees, Ineke, Gunst, Jan, Van Cromphaut, Sophie, Van den Berghe, Greet
格式: Artigo
語言:Inglês
出版: Springer International Publishing 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480347/
https://ncbi.nlm.nih.gov/pubmed/26215816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40635-015-0052-3
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