Critical illness-induced bone loss is related to deficient autophagy and histone hypomethylation

BACKGROUND: Survivors of critical illness are at increased risk of fractures. This may be due to increased osteoclast formation during critical illness, leading to trabecular bone loss. Such bone loss has also been observed in Paget’s disease, and has been related to deficient autophagy. Deficient a...

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Detalles Bibliográficos
Publicado en:Intensive Care Med Exp
Main Authors: Owen, Helen C, Vanhees, Ineke, Gunst, Jan, Van Cromphaut, Sophie, Van den Berghe, Greet
Formato: Artigo
Idioma:Inglês
Publicado: Springer International Publishing 2015
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480347/
https://ncbi.nlm.nih.gov/pubmed/26215816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40635-015-0052-3
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